You will find the list of publications in which the Nikon Imaging Centre @ Institut Curie-CNRS has been acknowledged.
In addition, some publications were co-authored by the Nikon Imaging Centre.
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Effective Removal of Boron from Aqueous Solutions by Inorganic Adsorbents: A Review.         
Lou XY, Yohai L, Boada R, Resina-Gallego M, Han D, Valiente M. Molecules. 2023 Dec 21;29(1):59. doi: 10.3390/molecules29010059. PMID: 38202645 Free PMC article. Review.        
Transfer learning for versatile and training free high content screening analyses.         
Corbe M, Boncompain G, Perez F, Del Nery E, Genovesio A. Sci Rep. 2023 Dec 18;13(1):22599. doi: 10.1038/s41598-023-49554-8. PMID: 38114550 Free PMC article.        
Autophagy as an innate immunity response against pathogens: a Tango dance.         
Aguilera MO, Delgui LR, Reggiori F, Romano PS, Colombo MI. FEBS Lett. 2024 Jan;598(1):140-166. doi: 10.1002/1873-3468.14788. Epub 2023 Dec 26. PMID: 38101809 Review.        
Extracellular vesicles and co-isolated endogenous retroviruses from murine cancer cells differentially affect dendritic cells.         
Cocozza F, Martin-Jaular L, Lippens L, Di Cicco A, Arribas YA, Ansart N, Dingli F, Richard M, Merle L, Jouve San Roman M, Poullet P, Loew D, Lévy D, Hendrix A, Kassiotis G, Joliot A, Tkach M, Théry C. EMBO J. 2023 Dec 11;42(24):e113590. doi: 10.15252/embj.2023113590. PMID: 38073509 Free PMC article.        
High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation.         
Laine RF, Heil HS, Coelho S, Nixon-Abell J, Jimenez A, Wiesner T, Martínez D, Galgani T, Régnier L, Stubb A, Follain G, Webster S, Goyette J, Dauphin A, Salles A, Culley S, Jacquemet G, Hajj B, Leterrier C, Henriques R. Nat Methods. 2023 Dec;20(12):1949-1956. doi: 10.1038/s41592-023-02057-w. Epub 2023 Nov 13. PMID: 37957430 Free PMC article.        
A mechanosensitive caveolae-invadosome interplay drives matrix remodelling for cancer cell invasion.         
Monteiro P, Remy D, Lemerle E, Routet F, Macé AS, Guedj C, Ladoux B, Vassilopoulos S, Lamaze C, Chavrier P. Nat Cell Biol. 2023 Dec;25(12):1787-1803. doi: 10.1038/s41556-023-01272-z. Epub 2023 Oct 30. PMID: 37903910 Free PMC article.        
Revealing invisible cell phenotypes with conditional generative modeling.         
Lamiable A, Champetier T, Leonardi F, Cohen E, Sommer P, Hardy D, Argy N, Massougbodji A, Del Nery E, Cottrell G, Kwon YJ, Genovesio A. Nat Commun. 2023 Oct 11;14(1):6386. doi: 10.1038/s41467-023-42124-6. PMID: 37821450 Free PMC article.        
Integrated High-Throughput Screening and Large-Scale Isobolographic Analysis to Accelerate the Discovery of Radiosensitizers With Greater Selectivity for Cancer Cells.         
Verrelle P, Gestraud P, Poyer F, Soria A, Tessier S, Lescure A, Anthony E, Corbé M, Heinrich S, Beauvineau C, Chaput L, Granzhan A, Piguel S, Perez F, Teulade-Fichou MP, Megnin-Chanet F, Del Nery E. Int J Radiat Oncol Biol Phys. 2023 Sep 29:S0360-3016(23)07958-0. doi: 10.1016/j.ijrobp.2023.09.044. Online ahead of print. PMID: 37778425        
Codependencies of mTORC1 signaling and endolysosomal actin structures.         
Priya A, Antoine-Bally S, Macé AS, Monteiro P, Sabatet V, Remy D, Dingli F, Loew D, Demetriades C, Gautreau AM, Chavrier P. Sci Adv. 2023 Sep 15;9(37):eadd9084. doi: 10.1126/sciadv.add9084. Epub 2023 Sep 13. PMID: 37703363 Free article.        
Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.         
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R. Nature. 2023 Sep;621(7978):415-422. doi: 10.1038/s41586-023-06506-6. Epub 2023 Sep 6. PMID: 37674080 Free PMC article. 

Medium-throughput image-based phenotypic siRNA screen to unveil the molecular basis of B cell polarization.         
Obino D, Maurin M, Dingli F, Loew D, Lescure A, Terriac E, Goudot C, Malbec O, Lankar D, Yuseff MI, Lennon-Duménil AM, Moreau HD. Sci Data. 2023 Jun 23;10(1):401. doi: 10.1038/s41597-023-02301-0. PMID: 37353541 Free PMC article.        
Presence of EBV antigens detected by a sensitive method in pediatric and adult Diffuse Large B-cell lymphomas.         
Mangiaterra TS, De Dios Soler M, Oviedo N, Colli S, Preciado MV, Soria M, Galluzo L, De Matteo E, Chabay P. Int J Cancer. 2023 Sep 1;153(5):1043-1050. doi: 10.1002/ijc.34623. Epub 2023 Jun 15. PMID: 37318089        
Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics.         
Fevre R, Mary G, Vertti-Quintero N, Durand A, Tomasi RF, Del Nery E, Baroud CN. iScience. 2023 Apr 12;26(5):106651. doi: 10.1016/j.isci.2023.106651. eCollection 2023 May 19. PMID: 37168549 Free PMC article.        
Characterization of Extracellular Vesicles by Transmission Electron Microscopy and Immunolabeling Electron Microscopy.         
Corona ML, Hurbain I, Raposo G, van Niel G. Methods Mol Biol. 2023;2668:33-43. doi: 10.1007/978-1-0716-3203-1_4. PMID: 37140788 Free article.  

Macromolecular sheets direct the morphology and orientation of plate-like biogenic guanine crystals.
Wagner A, Upcher A, Maria R, Magnesen T, Zelinger E, Raposo G, Palmer BA. Nat Commun. 2023 Feb 3;14(1):589. doi: 10.1038/s41467-023-35894-6. PMID: 36737617 Free PMC article.        
Invadopodia Methods: Detection of Invadopodia Formation and Activity in Cancer Cells Using Reconstituted 2D and 3D Collagen-Based Matrices.     
Remy D, Macé AS, Chavrier P, Monteiro P. Methods Mol Biol. 2023;2608:225-246. doi: 10.1007/978-1-0716-2887-4_14. PMID: 36653711        
Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models.         
Tucker ER, Jiménez I, Chen L, Bellini A, Gorrini C, Calton E, Gao Q, Che H, Poon E, Jamin Y, Martins Da Costa B, Barker K, Shrestha S, Hutchinson JC, Dhariwal S, Goodman A, Del Nery E, Gestraud P, Bhalshankar J, Iddir Y, Saberi-Ansari E, Saint-Charles A, Geoerger B, Marques Da Costa ME, Pierre-Eugène C, Janoueix-Lerosey I, Decaudin D, Nemati F, Carcaboso AM, Surdez D, Delattre O, George SL, Chesler L, Tweddle DA, Schleiermacher G. Clin Cancer Res. 2023 Apr 3;29(7):1317-1331. doi: 10.1158/1078-0432.CCR-22-2274. PMID: 36602782 Free PMC article.        
Removal of As(III) via adsorption and photocatalytic oxidation with magnetic Fe-Cu nanocomposites.         
Ayala LIM, Aparicio F, Boffa V, Magnacca G, Carlos L, Bosio GN, Mártire DO. Photochem Photobiol Sci. 2023 Mar;22(3):503-512. doi: 10.1007/s43630-022-00330-z. Epub 2022 Nov 3. PMID: 36327035        
How myosin VI traps its off-state, is activated and dimerizes.        
Canon L, Kikuti C, Planelles-Herrero VJ, Lin T, Mayeux F, Sirkia H, Lee YI, Heidsieck L, Velikovsky L, David A, Liu X, Moussaoui D, Forest E, Höök P, Petersen KJ, Morgan TE, Di Cicco A, Sirés-Campos J, Derivery E, Lévy D, Delevoye C, Sweeney HL, Houdusse A. Nat Commun. 2023 Oct 23;14(1):6732. doi: 10.1038/s41467-023-42376-2.        
VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites.         
Subra M, Dezi M, Bigay J, Lacas-Gervais S, Di Cicco A, Araújo ARD, Abélanet S, Fleuriot L, Debayle D, Gautier R, Patel A, Roussi F, Antonny B, Lévy D*, Mesmin B*. Dev Cell. 2023 Jan 23;58(2):121-138.e9. doi: 10.1016/j.devcel.2022.12.010.         
Galectin-3 Binding to α5β1 Integrin in Pore Suspended Biomembranes.        
Sarangi NK, Shafaq-Zadah M, Berselli GB, Robinson J, Dransart E, Di Cicco A, Lévy D, Johannes L, Keyes TE. J Phys Chem B. 2022 Dec 8;126(48):10000-10017. doi: 10.1021/acs.jpcb.2c05717.        
Direct observation of the conformational states of formin mDia1 at actin filament barbed ends and along the filament.        
Maufront J, Guichard B, Cao LY, di Cicco A, Jégou A, Romet-Lemonne G, Bertin A. Mol Biol Cell. 2023 Jan 1;34(1):ar2. doi: 10.1091/mbc.E22-10-0472.      

A human septin octamer complex sensitive to membrane curvature drives membrane deformation with a specific mesh-like organization.         
Nakazawa K, Kumar G, Chauvin B, Di Cicco A, Pellegrino L, Trichet M, Hajj B, Cabral J, Sain A, Mangenot S, Bertin A. J Cell Sci. 2023 Jun 1;136(11):jcs260813. doi: 10.1242/jcs.260813        
Reconstituted in vitro systems to reveal the roles and functions of septins.        
Nakazawa K, Chauvin B, Mangenot S, Bertin A. J Cell Sci. 2023 Oct 1;136(19):jcs259448. doi: 10.1242/jcs.259448.        
On the role of nucleotides and lipids in the polymerization of the actin homolog MreB from a Gram-positive bacterium.         
Mao W, Renner LD, Cornilleau C, Li de la Sierra-Gallay I, Afensiss S, Benlamara S, Ah-Seng Y, Van Tilbeurgh H, Nessler S, Bertin A, Chastanet A, Carballido-Lopez R. Elife. 2023 Oct 11;12:e84505. doi: 10.7554/eLife.84505.        
In Vitro Interaction of Melanoma-Derived Extracellular Vesicles with Collagen        
Roberta Palmulli , Enzo Bresteau , Graça Raposo , Guillaume Montagnac, Guillaume van Niel. Int J Mol Sci 2023 Feb 12;24(4):3703. doi: 10.3390/ijms24043703."        
Epithelial apoptotic pattern emerges from global and local regulation by cell apical area        
Victoire M L Cachoux , Maria Balakireva  , Mélanie Gracia , Floris Bosveld , Jesús M López-Gay  , Aude Maugarny , Isabelle Gaugué , Florencia di Pietro , Stéphane U Rigaud , Lorette Noiret , Boris Guirao , Yohanns Bellaïche 
Curr Biol 2023 Nov 20;33(22):4807-4826.e6. doi: 10.1016/j.cub.2023.09.049."        
Apical size and deltaA expression predict adult neuralstem cell decisions along lineage progression        
Mancini L, Guirao B, Ortica S, Labusch M, Cheysson F, Bonnet V, Phan MS, Herbert S, Mahou P, Menant E, Bedu S, Tinevez JY, Baroud C, Beaurepaire E, Bellaiche Y, Bally-Cuif L, Dray N. Sci Adv. 2023 Sep;9(35):eadg7519. doi: 10.1126/sciadv.adg7519.        
Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division    
"di Pietro F, Osswald M, De Las Heras JM, Cristo I, López-Gay J, Wang Z, Pelletier S, Gaugué I, Leroy A, Martin C, Morais-de-Sá E, Bellaïche Y.
Curr Biol  2023 Mar 13;33(5):858-874.e7. doi: 10.1016/j.cub.2023.01.028"        
Homeotic compartment curvature and tension control spatiotemporal folding dynamics        
Villedieu A, Alpar L, Gaugué I, Joudat A, Graner F, Bosveld F, Bellaïche Y. Nat Commun. 2023 Feb 3;14(1):594. doi: 10.1038/s41467-023-36305-6        
Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the polar body extrusion pathway        
Pelzer D, de Plater L, Bradbury P, Eichmuller A, Bourdais A, Halet G, Maître JL. EMBO J. 2023 Sep 4;42(17):e114415. doi: 10.15252/embj.2023114415. Epub 2023 Jul 10.        
Filopodia-like protrusions of adjacent somatic cells shape the developmental potential of oocytes                
Pelzer D, de Plater L, Bradbury P, Eichmuller A, Bourdais A, Halet G, Maître JL. EMBO J. 2023 Sep 4;42(17):e114415. doi: 10.15252/embj.2023114415. Epub 2023 Jul 10.        
N-BAR and F-BAR proteins—endophilin-A3 and PSTPIP1—control clathrin-independent endocytosis of L1CAM        
Lemaigre C, Ceuppens A, Valades-Cruz CA, Ledoux B, Vanbeneden B, Hassan M, Zetterberg FR, Nilsson UJ, Johannes L, Wunder C, Renard HF, Morsomme P. Traffic. 2023 Apr;24(4):190-212. doi: 10.1111/tra.12883.        
A synthetic delivery vector for mucosal vaccination        
Billet A, Hadjerci J, Tran T, Kessler P, Ulmer J, Mourier G, Ghazarian M, Gonzalez A, Thai R, Urquia P, Van Baelen AC, Meola A, Fernandez I, Deville-Foillard S, MacDonald E, Paolini L, Schmidt F, Rey FA, Kay MS, Tartour E, Servent D, Johannes L. Biomaterials. 2023 Nov;302:122298. doi: 10.1016/j.biomaterials.2023.122298.         
SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation        
Zhang C, Shafaq-Zadah M, Pawling J, Hesketh GG, Dransart E, Pacholczyk K, Longo J, Gingras AC, Penn LZ, Johannes L, Dennis JW. J Biol Chem. 2023 Dec;299(12):105416. doi: 10.1016/j.jbc.2023.105416. Epub 2023 Nov 2.        
A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution         
Chen YH, Tian W, Yasuda M, Ye Z, Song M, Mandel U, Kristensen C, Povolo L, Marques ARA, Čaval T, Heck AJR, Sampaio JL, Johannes L, Tsukimura T, Desnick R, Vakhrushev SY, Yang Z, Clausen H. Front Bioeng Biotechnol. 2023 Feb 24;11:1128371. doi: 10.3389/fbioe.2023.1128371. eCollection 2023.

A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production        
Gautier-Stein A, Chilloux J, Soty M, Thorens B, Place C, Zitoun C, Duchampt A, Da Costa L, Rajas F, Lamaze C, Mithieux G. Mol Metab. 2023 Apr;70:101700. doi: 10.1016/j.molmet.2023.101700. Epub 2023 Mar 2        
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK-STAT endosomal activation        
Zanin N, Viaris de Lesegno C, Podkalicka J, Meyer T, Gonzalez Troncoso P, Bun P, Danglot L, Chmiest D, Urbé S, Piehler J, Blouin CM, Lamaze C. Nat Cell Biol. 2023 Mar;25(3):425-438. doi: 10.1038/s41556-022-01085-6.        
Chromatin state transitions in the Drosophila intestinal lineage identify principles of cell-type specification        
Josserand M, Rubanova N, Stefanutti M, Roumeliotis S, Espenel M, Marshall OJ, Servant N, Gervais L, Bardin AJ. Dev Cell. 2023 Dec 18;58(24):3048-3063.e6. doi: 10.1016/j.devcel.2023.11.005.        
A fluorogenic chemically induced dimerization technology for controlling, imaging and sensing protein proximity        
Bottone S, Joliot O, Cakil ZV, El Hajji L, Rakotoarison LM, Boncompain G, Perez F, Gautier A. Nat Methods. 2023 Oct;20(10):1553-1562. doi: 10.1038/s41592-023-01988-8.        
DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C        
Kovacs MT, Vallette M, Wiertsema P, Dingli F, Loew D, Nader GPF, Piel M, Ceccaldi R. Mol Cell. 2023 Oct 19;83(20):3659-3668.e10. doi: 10.1016/j.molcel.2023.09.023. Epub 2023 Oct 12.        
Codependencies of mTORC1 signaling and endolysosomal actin structures        
Priya A, Antoine-Bally S, Macé AS, Monteiro P, Sabatet V, Remy D, Dingli F, Loew D, Demetriades C, Gautreau AM, Chavrier P. Sci Adv. 2023 Sep 15;9(37):eadd9084. doi: 10.1126/sciadv.add9084.        
Filopodia-like protrusions of adjacent somatic cells shape the developmental potential of oocytes         
Crozet F, Letort G, Bulteau R, Da Silva C, Eichmuller A, Tortorelli AF, Blévinal J, Belle M, Dumont J, Piolot T, Dauphin A, Coulpier F, Chédotal A, Maître JL, Verlhac MH, Clarke HJ, Terret ME. Life Sci Alliance. 2023 Mar 21;6(6):e202301963. doi: 10.26508/lsa.202301963        
In vivo tracking of functionally tagged Rad51 unveils a robust strategy of homology search        
Liu S, Miné-Hattab J, Villemeur M, Guerois R, Pinholt HD, Mirny LA, Taddei A. Nat Struct Mol Biol. 2023 Oct;30(10):1582-1591. doi: 10.1038/s41594-023-01065-w        



Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance. Lodillinsky, C; Fuhrmann, L; Irondelle, M; Pylypenko, O; Li, XY; Bonsang-Kitzis, H; Reyal, F; Vacher, S; Calmel, C; De Wever, O; Bieche, I; Lacombe, ML; Eijan, AM; Houdusse, A; Vincent-Salomon, A; Weiss, SJ; Chavrier, P; Boissan, M. Oncogene. 2021 Jun;40(23):4019-4032. doi: 10.1038/s41388-021-01826-1.


HPM live μ for a full CLEM workflow. Heiligenstein X, De Beer M, Heiligenstein J, Eyraud F, Manet L, Schmitt F, Lamers E, Lindenau J, Kea-Te Lindert M, Salamero J, Raposo G, Sommerdijk N, Belle M, Akiva A. Methods Cell Biol. 2021; 162:115-149. doi:10.1016/bs.mcb.2020.10.022.


Absolute Quantification of Drug Vector Delivery to the Cytosol. Lucchino, M; Billet, A; Bai, SK; Dransart, E; Hadjerci, J; Schmidt, F; Wunder, C; Johannes, L. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021 Jun 25;60(27):14824-14830. doi: 10.1002/anie.202102332.


Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes. Ivashenka, A; Wunder, C; Chambon, V; Sandhoff, R; Jennemann, R; Dransart, E; Podsypanina, K; Lombard, B; Loew, D; Lamaze, C; Poirier, F; Grone, HJ; Johannes, L; Shafaq-Zadah, M. Commun Biol. 2021 Feb 9;4(1):173. doi: 10.1038/s42003-021-01693-2.


Ceramide structure dictates glycosphingolipid nanodomain assembly and function. Arumugam, S; Schmieder, S; Pezeshkian, W; Becken, U; Wunder, C; Chinnapen, D; Ipsen, JH; Kenworthy, AK; Lencer, W; Mayor, S; Johannes, L. . Nat Commun. 2021 Jun 16;12(1):3675. doi: 10.1038/s41467-021-23961-9.


Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism. Saez J.J, Dogniaux S, Shafaq-Zadah M, Johannes L, Hivroz C, Zucchetti  A.E. Retrograde and Anterograde Transport of Lat-Cells. 2021 Feb 9;10(2):359. doi: 10.3390/cells10020359.


Longitudinal high-resolution imaging through a flexible intravital imaging window. Jacquemin G, Benavente-Diaz M, Djaber S, Bore A, Dangles-Marie V, Surdez D, Tajbakhsh S, Fre S, Lloyd-Lewis B. Sci Adv. 2021 Jun 16;7(25): eabg7663. doi:10.1126/sciadv.abg7663


CAMSAPs organize an acentrosomal microtubule network from basal varicosities in radial glial cells. Laure Coquand , Guiliana Soraya Victoria , Alice Tata, Jacopo Amerigo Carpentieri, Jean-Baptiste Brault, Fabien Guimiot, Vincent Fraisier, Alexandre D Baffet. J Cell Biol. 2021 Aug 2;220(8):e202003151. doi: 10.1083/jcb.202003151.


The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization. Alqabandi, M; de Franceschi, N; Maity, S; Miguet, N; Bally, M; Roos, WH; Weissenhorn, W; Bassereau, P; Mangenot, S. BMC BIOLOGY, 2021 Apr 8;19(1):66, doi: 10.1186/s12915-021-00983-9.



A new pipeline for pathophysiological analysis of the mammary gland based on organoid transplantation and organ clearing. Lagoutte E, Villeneuve C, Fraisier V, Krndija D, Deugnier M-A, Chavrier P, Rossé C.  J Cell Sci. 2020 Jun 23;133(12):jcs242495. doi: 10.1242/jcs.242495.


Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation. Domingues, L; Hurbain, I; Gilles-Marsens, F; Sires-Campos, J; Andr, N; Dewulf, M; Romao, M; de Lesegno, CV; Mac, AS; Blouin, C; Guere, C; Vi, K; Raposo, G; Lamaze, C; Delevoye, C. Nat Commun. 2020 Jun 12;11(1):2988. doi: 10.1038/s41467-020-16738-z.


RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5. Cayre S, Faraldo M.M, Bardin S, Miserey-Lenkei S, Deugnier M-A, Goud B. Development . 2020 Oct 8;147(19):dev190744. doi: 10.1242/dev.190744.


Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166. Renard, HF; Tyckaert, F; Lo Giudice, C; Hirsch, T; Valades-Cruz, CA; Lemaigre, C; Shafaq-Zadah, M; Wunder, C; Wattiez, R; Johannes, L; van der Bruggen, P; Alsteens, D; Morsomme, P.  Nat Commun. 2020 Mar 19;11(1):1457. doi: 10.1038/s41467-020-15303-y


Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2. Forrester, A; Rathjen, SJ; Garcia-Castillo, MD; Bachert, C; Couhert, A; Tepshi, L; Pichard, S; Martinez, J; Munier, M; Sierocki, R; Renard, HF; Valades-Cruz, CA; Dingli, F; Loew, D; Lamaze, C; Cintrat, JC; Linstedt, AD; Gillet, D; Barbier, J; Johannes, L. Nat Chem Biol. 2020 Mar;16(3):327-336. doi: 10.1038/s41589-020-0474-4.


EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma. Shen, WW; Bieche, I; Fuhrmann, L; Vacher, S; Vincent-Salomon, A; Torrino, S; Lamaze, C. Sci Rep. 2020 May 14;10(1):7998. doi: 10.1038/s41598-020-65054-5.


Study of Caveolae-Dependent Mechanoprotection in Human Muscle Cells Using Micropatterning and Live-Cell Microscopy CAVEOLAE. Dewulf, M; Blouin, CM. Methods and Protocols, Methods in Molecular Biology, 2020, 2169, 189-196, doi : : 10.1007/978-1-0716-0732-9_17


Quantifying Spatiotemporal Parameters of Cellular Exocytosis in Micropatterned Cells. Lachuer, H; Mathur, P; Bleakley, K; Schauer, K. JVis Exp 2020 Sep 16;(163), doi: 10.3791/60801.


GPMVs as a Tool to Study Caveolin-Interacting Partners CAVEOLAE. Podkalicka, J; Blouin, CM. Methods Mol Biol,2020;2169:81-88., doi: 10.1007/978-1-0716-0732-9_8.


Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia. Zagryazhskaya-Masson, A; Monteiro, P; Mace, AS; Castagnino, A; Ferrari, R; Infante, E; Duperray-Susini, A; Dingli, F; Lanyi, A; Loew, D; Genot, E; Chavrier, P. JCB. 2020 Sep 7;219(9):e201910132. doi: 10.1083/jcb.201910132.


Nesprin-2 accumulates at the front of the nucleus during confined cell migration. Davidson, PM; Battistella, A; Dejardin, T; Betz, T; Plastino, J; Borghi, N; Cadot, B; Sykes, C. EMBO Report, 2020 Jul 3;21(7):e49910.doi: 10.15252/embr.201949910. Epub 2020 May 17.


Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms. Pelon, F; Bourachot, B; Kieffer, Y; Magagna, I; Mermet-Meillon, F; Bonnet, I; Costa, A; Givel, AM; Attieh, Y; Barbazan, J; Bonneau, C; Fuhrmann, L; Descroix, S; Vignjevic, D; Silberzan, P; Parrini, MC; Vincent-Salomon, A; Mechta-Grigoriou, F.  Nat Commun. 2020 Jan 21;11(1):404., doi: 10.1038/s41467-019-14134-w.


Traction Force Microscopy to Study B Lymphocyte Activation. Kumari, A; Pineau, J; Lennon-Dumenil, AM; Balland, M; Pierobon, P.  J Vis Exp. 2020 Jul 23;(161). doi: 10.3791/60947.



aPKCi triggers basal extrusion of luminal mammary epithelial cells by tuning contractility and vinculin localization at cell junctions. Villeneuve, C; Lagoutte, E; de Plater, L; Mathieu, S; Manneville, JB; Maitre, JL; Chavrier, P; Rosse, C. PNAS 0027-8424, NOV 26, 2019, 116, 48, 24108, 24114, 10.1073,doi: 10.1073/pnas.1906779116.


P. MT1-MMP directs force-producing proteolytic contacts that drive tumor cell invasion. Ferrari, R; Martin, G; Tagit, O; Guichard, A; Cambi, A; Voituriez, R; Vassilopoulos, S; Chavrier,   Nat Commun. 2019 Oct 25;10(1):4886, doi: 10.1038/s41467-019-12930-y


Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo. Verweij, FJ; Revenu, C; Arras, G; Dingli, F; Loew, D; Pegtel, DM; Follain, G; Allio, G; Goetz, JG; Zimmermann, P; Herbomel, P; Del Bene, F; Raposo, G; van Niel, G. Dev Cell. 2019 Feb 25;48(4):573-589.e4, doi: 10.1016/j.devcel.2019.01.004


Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells. Dewulf, M; Koster, DV; Sinha, B; de Lesegno, CV; Chambon, V; Bigot, A; Bensalah, M; Negroni, E; Tardif, N; Podkalicka, J; Johannes, L; Nassoy, P; Butler-Browne, G; Lamaze, C; Blouin, CM. Nat Commun. 2019 Apr 29;10(1):1974. doi: 10.1038/s41467-019-09405-5.


The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation. Bissig C, Croisé P, Heiligenstein X, Hurbain I, Lenk GM, Kaufman E, Sannerud R, Wim Annaert W, Meisler MH, Weisman LS, Raposo G, Van Niel G. J Cell Sci. 2019 Feb 28;132(5):jcs229500. doi: 10.1242/jcs.229500.


MYO1C stabilizes actin and facilitates the arrival of transport carriers at the Golgi complex. Capmany A, Yoshimura A, Kerdous R, Caorsi V, Lescure A, Elaine Del Nery E, Coudrier E, Goud B, Schauer K. J Cell Sci. 2019 Apr 26;132(8):jcs225029. doi: 10.1242/jcs.225029.


Differences in Mitotic Spindle Architecture in Mammalian Neural Stem Cells Influence Mitotic Accuracy during Brain Development. Vargas-Hurtado D, Brault JB, Piolot T, Leconte L, Da Silva N, Pennetier C, Baffet A, Marthiens V, Basto R . Curr Biol. 2019 Sep 23;29(18):2993-3005.e9. doi: 10.1016/j.cub.2019.07.061.


Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma. Job, S; Draskovic, I; Burnichon, N; Buffet, A; Cros, J; Lepine, C; Venisse, A; Robidel, E; Verkarre, V; Meatchi, T; Sibony, M; Amar, L; Bertherat, J; de Reynies, A; Londono-Vallejo, A; Favier, J; Castro-Vega, LJ; Gimenez-Roqueplo, AP.  Clin Cancer Res. 2019 Jan 15;25(2):760-770. doi: 10.1158/1078-0432.CCR-18-0139.


Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse. Zucchetti, AE; Bataille, L; Carpier, JM; Dogniaux, S; Roman-Jouve, MS; Maurin, M; Stuck, MW; Rios, RM; Baldari, CT; Pazour, GJ; Hivroz, C. Nat Commun. 2019 Jun 28;10(1):2864. doi: 10.1038/s41467-019-10891-w.


Actomyosin-driven force patterning controls endocytosis at the immune synapse. Kumari, A; Pineau, J; Saez, PJ; Maurin, M; Lankar, D; San Roman, M; Hennig, K; Boura, VF; Voituriez, R; Karlsson, MCI; Balland, M; Dumenil, AML; Pierobon, P. Nat Commun. 2019 Jun 28;10(1):2870. doi: 10.1038/s41467-019-10751-7.



Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function. Castagnino, A; Castro-Castro, A; Irondelle, M; Guichard, A; Lodillinsky, C; Fuhrmann, L; Vacher, S; Aguera-Gonzalez, S; Zagryazhskaya-Masson, A; Romao, M; El Kesrouani, C; Noegel, AA; Dubois, T; Raposo, G; Bear, JE; Clemen, CS; Vincent-Salomon, A; Bieche, I; Chavrier, P. Oncogene. 2018 Dec;37(50):6425-6441. doi: 10.1038/s41388-018-0422-x.


LINC complex-Lisl interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration. Infante, E; Castagnino, A; Ferrari, R; Monteiro, P; Aguera-Gonzalez, S; Paul-Gilloteaux, P; Domingues, MJ; Maiuri, P; Raab, M; Shanahan, CM; Baffet, A; Piel, M; Gomes, ER; Chavrier, P. Nat Commun. 2018 Jun 22;9(1):2443.doi: 10.1038/s41467-018-04865-7.


Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling. Verweij, FJ; Bebelman, MP; Jimenez, CR; Garcia-Vallejo, JJ; Janssen, H; Neefjes, J; Knol, JC; de Goeij-de Haas, R; Piersma, SR; Baglio, SR; Verhage, M; Middeldorp, JM; Zomer, A; van Rheenen, J; Coppolino, MG; Hurbain, I; Raposo, G; Smit, MJ; Toonen, RFG; van Niel, G; Pegtel, DM. J Cell Biol. 2018 Mar 5;217(3):1129-1142.doi: 10.1083/jcb.201703206.


Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers. Léa Ripoll 1, Xavier Heiligenstein 1, Ilse Hurbain 1 2, Lia Domingues 1, Florent Figon 1 3, Karl J Petersen 4, Megan K Dennis 5 6, Anne Houdusse 4, Michael S Marks 5 6, Graça Raposo 1 2, Cédric Delevoye. J Cell Biol. 2018 Aug 6;217(8):2709-2726.doi: 10.1083/jcb.201709055.


ABCB6 Resides in Melanosomes and Regulates Early Steps of Melanogenesis Required for PMEL Amyloid Matrix Formation. Bergam, P; Reisecker, JM; Rakvacs, Z; Kucsma, N; Raposo, G; Szakacs, G; van Niel, G.  J Mol Biol. 2018 Oct 12;430(20):3802-3818. doi: 10.1016/j.jmb.2018.06.033.


Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. Carpier, JM; Zucchetti, AE; Bataille, L; Dogniaux, S; Shafaq-Zadah, M; Bardin, S; Lucchino, M; Maurin, M; Joannas, LD; Magalhaes, JG; Johannes, L; Galli, T; Goud, B; Hivroz, C.  J Exp Med. 2018 Apr 2;215(4):1245-1265. doi: 10.1084/jem.20162042.


EHD2 is a mechanotransducer connecting caveolae dynamics with gene transcription. Torrino, S; Shen, WW; Blouin, CM; Mani, SK; de Lesegno, CV; Bost, P; Grassart, A; Koster, D; Valades-Cruz, CA; Chambon, V; Johannes, L; Pierobon, P; Soumelis, V; Coirault, C; Vassilopoulos, S; Lamaze, C. J Cell Biol. 2018 Dec 3;217(12):4092-4105. doi: 10.1083/jcb.201801122.


Engineering small tubes with changes in diameter for the study of kidney cell organization. Venzac, B; Madoun, R; Benarab, T; Monnier, S; Cayrac, F; Myram, S; Leconte, L; Amblard, F; Viovy, JL; Descroix, S; Coscoy, S. Biomicrofluidics. 2018 Apr 3;12(2):024114. doi: 10.1063/1.5025027. 


Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. Costa, A; Kieffer, Y; Scholer-Dahirel, A; Pelon, F; Bourachot, B; Cardon, M; Sirven, P; Magagna, I; Fuhrmann, L; Bernard, C; Bonneau, C; Kondratova, M; Kuperstein, I; Zinovyev, A; Givel, AM; Parrini, MC; Soumelis, V; Vincent-Salomon, A; Mechta-Grigoriou, F. Cancer Cell. 2018 Mar 12;33(3):463-479.e10.doi: 10.1016/j.ccell.2018.01.011.


AP-1/KIF13A Blocking Peptides Impair Melanosome Maturation and Melanin Synthesis. Campagne, C; Ripoll, L; Gilles-Marsens, F; Raposo, G; Delevoye, C. Int J Mol Sci. 2018 Feb 14;19(2):568.doi: 10.3390/ijms19020568.


Microtopographies control the development of basal protrusions in epithelial sheets. Coscoy, S; Baiz, S; Octon, J; Rhone, B; Perquis, L; Tseng, QZ; Amblard, F; Semetey, V. Biointerphases. 2018 Jun 8;13(4):041003.doi: 10.1116/1.5024601.


Spontaneous migration of cellular aggregates from giant keratocytes to running spheroids. Beaune, G; Blanch-Mercader, C; Douezan, S; Dumond, J; Gonzalez-Rodriguez, D; Cuvelier, D; Ondarcuhu, T; Sens, P; Dufour, S; Murrell, MP; Brochard-Wyart, F. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):12926-12931. doi: 10.1073/pnas.1811348115.    


The epigenetic control of stemness in CD8(+) T cell fate commitment. Pace, L; Goudot, C; Zueva, E; Gueguen, P; Burgdorf, N; Waterfall, JJ; Quivy, JP; Almouzni, G; Amigorena, S. Science. 2018 Jan 12;359(6372):177-186.doi: 10.1126/science.aah6499.


Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts. De Pascalis, C; Perez-Gonzalez, C; Seetharaman, S; Boeda, B; Vianay, B; Burute, M; Leduc, C; Borghi, N; Trepat, X; Etienne-Manneville, S. Science. 2018 Jan 12;359(6372):177-186.doi: 10.1126/science.aah6499.


Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse. Obino, D; Fetler, L; Soza, A; Malbec, O; Saez, JJ; Labarca, M; Oyanadel, C; Batalla, FD; Goles, N; Chikina, A; Lankar, D; Segovia-Miranda, F; Garcia, C; Leger, T; Gonzalez, A; Espeli, M; Lennon-Dumenil, AM; Yuseff, MI. Cell Rep. 2018 Dec 11;25(11):3110-3122.e6. doi: 10.1016/j.celrep.2018.11.052.


Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment. Bennabi, I; Queguiner, I; Kolano, A; Boudier, T; Mailly, P; Verlhac, MH; Terret, ME. EMBO Rep. 2018 Feb;19(2):368-381. doi: 10.15252/embr.201745225


A new biomimetic assay reveals the temporal role of matrix stiffening in cancer cell invasion. Staneva, R; Burla, F; Koenderink, GH; Descroix, S; Vignjevic, DM; Attieh, Y; Verhulsel, M. Mol Biol Cell. 2018 Dec 1;29(25):2979-2988. doi: 10.1091/mbc.E18-01-0068



Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Patwardhan, A; Bardin, S; Miserey-Lenkei, S; Larue, L; Goud, B; Raposo, G; Delevoye, C. Nat Commun. 2017 Jun 13;8:15835.doi: 10.1038/ncomms15835.


eC-CLEM: A multidimension, multimodel software to correlate intermodal images with a focus on light and electron microscopy. Xavier Heiligenstein, Perrine Paul-Gilloteaux, Graça Raposo, Jean Salamero. Methods Cell Biol. 2017;140:335-352.doi: 10.1016/bs.mcb.2017.03.014.


Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells. Franzetti, GA; Laud-Duval, K; van der Ent, W; Brisac, A; Irondelle, M; Aubert, S; Dirksen, U; Bouvier, C; de Pinieux, G; Snaar-Jagalska, E; Chavrier, P; Delattre, O.  Oncogene. 2017 Jun 22;36(25):3505-3514. doi: 10.1038/onc.2016.498.


Cancer-associated fibroblasts lead tumor invasion through integrin-beta 3-dependent fibronectin assembly. Attieh, Y; Clark, AG; Grass, C; Richon, S; Pocard, M; Mariani, P; Elkhatib, N; Betz, T; Gurchenkov, B; Vignjevic, DM. J Cell Biol. 2017 Nov 6;216(11):3509-3520. doi: 10.1083/jcb.201702033.


Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions. Miserey-Lenkei, S; Bousquet, H; Pylypenko, O; Bardin, S; Dimitrov, A; Bressanelli, G; Bonifay, R; Fraisier, V; Guillou, C; Bougeret, C; Houdusse, A; Echard, A; Goud, B. Nat Commun. 2017 Nov 1;8(1):1254. doi: 10.1038/s41467-017-01266-0


Mechanism of Shiga Toxin Clustering on Membranes. Pezeshkian, W; Gao, HF; Arumugam, S; Becken, U; Bassereau, P; Florent, JC; Ipsen, JH; Johannes, L; Shillcock, JC. ACS Nano. 2017 Jan 24;11(1):314-324. doi: 10.1021/acsnano.6b05706



AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin. Couderc C, Boin A, Fuhrmann L, Vincent-Salomon A, Mandati V, Kieffer Y, Mechta-Grigoriou F, Del Maestro L, Chavrier P, Vallerand D, Brito I, Dubois T, De Koning L, Bouvard D, Louvard D, Gautreau A, Lallemand D. Neoplasia. 2016 Jan;18(1):10-24. doi: 10.1016/j.neo.2015.11.010.


BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers. Dennis MK, Delevoye C, Acosta-Ruiz A, Hurbain I, Romao M, Hesketh GG, Goff PS, Sviderskaya EV, Bennett DC, Luzio JP, Galli T, Owen DJ, Raposo G, Marks MS. J Cell Biol. 2016 Aug 1;214(3):293-308. doi: 10.1083/jcb.201605090.


BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes. Delevoye C, Heiligenstein X, Ripoll L, Gilles-Marsens F, Dennis MK, Linares RA, Derman L, Gokhale A, Morel E, Faundez V, Marks MS, Raposo G. Curr Biol. 2016 Jan 11;26(1):1-13.doi: 10.1016/j.cub.2015.11.020


Persistent cell migration and adhesion rely on retrograde transport of β(1) integrin. Shafaq-Zadah M, Gomes-Santos CS, Bardin S, Maiuri P, Maurin M, Iranzo J, Gautreau A, Lamaze C, Caswell P, Goud B, Johannes L. Nat Cell Biol. 2016 Jan;18(1):54-64. doi: 10.1038/ncb3287.


Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex. Chmiest D, Sharma N, Zanin N, Viaris de Lesegno C, Shafaq-Zadah M, Sibut V, Dingli F, Hupé P, Wilmes S, Piehler J, Loew D, Johannes L, Schreiber G, Lamaze C. Nat Commun. 2016 Dec 5;7:13476. doi: 10.1038/ncomms13476.


IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Vivar OI, Masi G, Carpier JM, Magalhaes JG, Galgano D, Pazour GJ, Amigorena S, Hivroz C, Baldari CT. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):386-91.doi: 10.1073/pnas.1513601113.


Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage. Técher H, Koundrioukoff S, Carignon S, Wilhelm T, Millot GA, Lopez BS, Brison O, Debatisse M. Cell Rep. 2016 Feb 9;14(5):1114-1127. doi: 10.1016/j.celrep.2015.12.093


Actin nucleation at the centrosome controls lymphocyte polarity. Obino D, Farina F, Malbec O, Sáez PJ, Maurin M, Gaillard J, Dingli F, Loew D, Gautreau A, Yuseff MI, Blanchoin L, Théry M, Lennon-Duménil AM. Nat Commun. 2016 Mar 18;7:10969.doi: 10.1038/ncomms10969.


Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen. Sedlik C, Heitzmann A, Viel S, Ait Sarkouh R, Batisse C, Schmidt F, De La Rochere P, Amzallag N, Osinaga E, Oppezzo P, Pritsch O, Sastre-Garau X, Hubert P, Amigorena S, Piaggio E. Oncoimmunology. 2016 Apr 22;5(7):e1171434.doi: 10.1080/2162402X.2016.1171434.


Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments. Thiam HR, Vargas P, Carpi N, Crespo CL, Raab M, Terriac E, King MC, Jacobelli J, Alberts AS, Stradal T, Lennon-Dumenil AM, Piel M. Nat Commun. 2016 Mar 15;7:10997. doi: 10.1038/ncomms10997.


LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP. Lagoutte E, Villeneuve C, Lafanechère L, Wells CM, Jones GE, Chavrier P, Rossé C. Sci Rep. 2016 Apr 27;6:24925. doi: 10.1038/srep24925.


Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion. Kopanska KS, Alcheikh Y, Staneva R, Vignjevic D, Betz T. PLoS One. 2016 Jun 7;11(6):e0156442.doi: 10.1371/journal.pone.0156442.


Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin. Broders-Bondon F, Paul-Gilloteaux P, Gazquez E, Heysch J, Piel M, Mayor R, Lambris JD, Dufour S. Dev Biol. 2016 Jun 1;414(1):85-99. doi: 10.1016/j.ydbio.2016.03.022.


Endothelin-3 stimulates cell adhesion and cooperates with β1-integrins during enteric nervous system ontogenesis. Gazquez E, Watanabe Y, Broders-Bondon F, Paul-Gilloteaux P, Heysch J, Baral V, Bondurand N, Dufour S. Sci Rep. 2016 Dec 1;6:37877.doi: 10.1038/srep37877.


Ligand-receptor dissociated expression explains high TSLP without prognostic impact in human primary head and neck squamous cell carcinoma. Guillot-Delost M, Guilleré L, Berger F, Ventre A, Michea P, Sirven P, Pattarini L, Scholer-Dahirel A, Kebir FZ, Huerre M, Chouchane-Mlik O, Lappartient E, Rodriguez J, Jouffroy T, Klijanienko J, Nicolas A, Sastre-Garau X, Honorio S, Mosseri V, Le Peltier N, Sablin MP, Le Tourneau C, Tartour É, Badoual C, Soumelis V. Oncoimmunology. 2016 Jun 7;5(7):e1179414.doi: 10.1080/2162402X.2016.1179414.


Polycystins and intercellular mechanotransduction: A precise dosage of polycystin 2 is necessary for alpha-actinin reinforcement of junctions upon mechanical stimulation.Bhoonderowa L, Hameurlaine F, Arbabian A, Faqir F, Amblard F, Coscoy S. Exp Cell Res. 2016 Oct 15;348(1):23-35. doi: 10.1016/j.yexcr.2016.08.021.


Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation. Blouin CM, Hamon Y, Gonnord P, Boularan C, Kagan J, Viaris de Lesegno C, Ruez R, Mailfert S, Bertaux N, Loew D, Wunder C, Johannes L, Vogt G, Contreras FX, Marguet D, Casanova JL, Galès C, He HT, Lamaze C. Cell. 2016 Aug 11;166(4):920-934.doi: 10.1016/j.cell.2016.07.003. 


Localized Mechanical Stress Promotes Microtubule Rescue. De Forges H, Pilon A, Cantaloube I, Pallandre A, Haghiri-Gosnet AM, Perez F, Poüs C. Curr Biol. 2016 Dec 19;26(24):3399-3406.doi: 10.1016/j.cub.2016.10.048.


TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking. Varthaman A, Moreau HD, Maurin M, Benaroch P. PLoS One. 2016 Dec 2;11(12):e0167057.doi: 10.1371/journal.pone.0167057.


Posttranslational marks control architectural and functional plasticity of the nuclear pore complex basket. Niño CA, Guet D, Gay A, Brutus S, Jourquin F, Mendiratta S, Salamero J, Géli V, Dargemont C. J Cell Biol. 2016 Jan 18;212(2):167-80.doi: 10.1083/jcb.201506130


Persistent cell migration and adhesion rely on retrograde transport of β1 integrin. Shafaq-Zadah M, Gomes-Santos C S., Bardin S, Maiuri P, Maurin M, Iranzo J, Gautreau A, Lamaze C, Caswell P, Bruno Goud B and Johannes L. Nat Cell Biol. 2016 Jan;18(1):54-64. doi: 10.1038/ncb3287. 



Phenotypic characterisation of RAB6A knockout mouse embryonic fibroblasts. Bardin S, Miserey-Lenkei S, Hurbain I, Garcia-Castillo M D, Raposo G and Goud B. Biol Cell. 2015 Dec;107(12):427-39.doi: 10.1111/boc.201400083.


Integrin endosomal signalling suppresses anoikis.Alanko J, Mai A, Jacquemet G, Schauer K, Kaukonen R, Saari M, Goud B and Ivaska J. Nat Cell Biol. 2015 Nov;17(11):1412-21.doi: 10.1038/ncb3250.


Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin. Garcia-Castillo MD, Tran T, Bobard A, Renard H-F, Rathjen S J., Dransart E, Stechmann B, Lamaze C, Lord M, Cintrat J-C, Enninga J, Tartour E and Johannes L. J Cell Sci. 2015 Jul 1;128(13):2373-87.doi: 10.1242/jcs.169383.


Shiga toxin stimulates clathrin-independent endocytosis of the VAMP2, VAMP3 and VAMP8 SNARE proteins. Renard H-F, Garcia-Castillo M D, Chambon V, Lamaze C, and Johannes L.  J Cell Sci. 2015 Aug 1;128(15):2891-902.doi: 10.1242/jcs.171116.


Quantitative analysis of flagellar proteins in Drosophila sperm tails. Maia T M, Paul-Gilloteaux P and Basto R. Methods Cell Biol. 2015;127:263-78.doi: 10.1016/bs.mcb.2015.01.003


ARF6–JIP3/4 regulate endosomal tubules for MT1- MMP exocytosis in cancer invasion. Marchesin V, Castro-Castro A, Lodillinsky C, Castagnino A, Cyrta J, Bonsang-Kitzis H, Fuhrmann L, Irondelle M, Infante E, Montagnac G, Reyal F, Vincent-Salomon A and Philippe Chavrier P. J Cell Biol. 2015 Oct 26;211(2):339-58. doi: 10.1083/jcb.201506002.


New insights into centrosome imaging in Drosophila and mouse neuroepithelial tissues. Rujano M A., Basto R and Marthiens V. Methods Cell Biol. 2015;129:211-227.doi: 10.1016/bs.mcb.2015.04.005.


Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA. Schertzer M, Jouravleva K, Perderiset M, Dingli F, Loew D, Le Guen T, Bardoni B, De Villartay J-P, Revy P and Londono-Vallejo A. Nucleic Acids Res. 2015 Feb 18;43(3):1834-47.doi: 10.1093/nar/gku1402.


Endophilin-A-2 functions in membrane scission in clathrin-independent endocytosis. Renard H-F, Simunovic M, Lemière J, Boucrot E, Garcia-Castillo M D, Arumugam S, Chambon V, Lamaze C, Wunder C, Kenworthy A K., Schmidt A A., McMahon H T., Sykes C, Bassereau P and Johannes L. Nature. 2015 Jan 22;517(7535):493-6. doi: 10.1038/nature14064.


The SENP7 SUMO-protease presents a module of two HP1 interaction motifs that locks HP1 protein at pericentric heterochromatin. Romeo K, Louault Y, Cantaloube S, Loiodice I, Almouzni G and Quivy J-P. Cell Rep. 2015 Feb 10;10(5):771-782. doi: 10.1016/j.celrep.2015.01.004.


Background fluorescence estimation and vesicle segmentation in live cell Imaging with conditional random fields. Pécot T, Bouthemy P, Boulanger J, Chessel A, Bardin S, Salamero J, and Kervrann C. IEEE Trans Image Process. 2015 Feb;24(2):667-80.doi: 10.1109/TIP.2014.2380178.


Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells. Liu Y-J, Le Berre M, Lautenschlaeger F, Maiuri P, Callan-Jones A, Heuzé M, Takaki T, Voituriez R  and Piel M. Cell. 2015 Feb 12;160(4):659-672.doi: 10.1016/j.cell.2015.01.007.


ARF6 Promotes the Formation of Rac1 and WAVE-dependent ventral F-Actin rosettes in breast cancer cells in response to epidermal growth factor. Marchesin V, Montagnac G and Chavrier P. PLoS One. 2015 Mar 23;10(3):e0121747.doi: 10.1371/journal.pone.0121747.


Moesin Is a Major Regulator of Centrosome Behavior in Epithelial Cells with Extra Centrosomes. Sabino D, Gogendeau D, Gambarotto D, Nano M, Pennetier C, Dingli F, Arras G, Loew D and Basto R. Curr Biol. 2015 Mar 30;25(7):879-89.doi: 10.1016/j.cub.2015.01.066.


Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Reversat A, Yuseffa M-I, Lankara D, Malbeca O, Obino D, Maurin M, Gayathri Penmatcha N V, Amorosoa A, Sengmanivong L, Gundersen G G., Mellman I, Darchen F, Desnos C, Pierobon P and Lennon-Duménila A-M. Mol Biol Cell. 2015 Apr 1;26(7):1273-85.doi: 10.1091/mbc.E14-09-1373.


Actin flows mediate a universal coupling between cell speed and cell persistence. Maiuri P, Rupprecht J-F, Wieser S, Ruprecht V, Bénichou O, Carpi N,Coppey M, De Beco S, Gov N, Heisenberg C-P, Lage Crespo C, Lautenschlaeger F, Le Berre M,Lennon-Dumenil A-M, Raab M,Thiam H-R,Piel M, Sixt M and Voituriez R. Cell. 2015 Apr 9;161(2):374-86.doi: 10.1016/j.cell.2015.01.056.


Mechanosensitive adaptation of E-Cadherin turnover across adherens Junctions. De Beco S, Perney J-B, Coscoy S and Amblard F. PLoS One. 2015 Jun 5;10(6):e0128281.doi: 10.1371/journal.pone.0128281.


Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Chabaud M, L. Heuzé M, Bretou M, Vargas P, Maiuri P, Solanes P, Maurin M, Terriac E, Le Berre M, Lankar D, Piolot T, Adelstein R S, Zhang Y, Sixt M, Jacobelli J, Bénichou O, Voituriez R, Piel M & Lennon-Duménil A-M. Nat Commun. 2015 Jun 25;6:7526.doi: 10.1038/ncomms8526.


Paracrine Met signaling triggers epithelial–mesenchymal transition in mammary luminal progenitors, affecting their fate. Di-Cicco A, Petit A, Chiche A, Bresson L, Romagnoli M, Orian-Rousseau V, Vivanco M, Medina D, Faraldo M, Glukhova M and Deugnier M-A.Elife. 2015 Jul 13;4:e06104. doi: 10.7554/eLife.06104.


Exosomes released by keratinocytes modulate melanocyte pigmentation. Lo Cicero A, Delevoye C, Gilles-Marsens F, Loew D, Dingli F, Guéré C, André N, Vié K, Van Niel G and Raposo. Nat Commun. 2015 Jun 24;6:7506. doi: 10.1038/ncomms8506


Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells. Van Niel G, Bergam P, Di Cicco A, Hurbain I,  Lo Cicero A, Dingli F, Palmulli R,  Fort C, Potier M-C, Schurgers L J., Loew D, Levy D and Raposo G. Cell Rep. 2015 Oct 6;13(1):43-51.doi: 10.1016/j.celrep.2015.08.057


Nanobody-functionalized PEG-b-PCL polymersomes and their targeting study. Zou T, Dembelea F, Beugnet F, Sengmanivong L, Trepout S, Marco S, De Marco A and Min-Hui Li M-H. J Biotechnol. 2015 Nov 20;214:147-55.doi: 10.1016/j.jbiotec.2015.09.034.


Aneuploidy causes premature differentiation of neural and intestinal stem cells. Gogendeau D, Siudeja K, Gambarotto D, Pennetier C, Bardin A J. and Basto R. Nat Commun. 2015 Nov 17;6:8894. doi: 10.1038/ncomms9894.


Combining Spinach-tagged RNA and gene localization to image gene expression in live yeast. Guet D, Burns L T., Maji S, Boulanger J, Hersen P, Wente S R, Salamero J and Dargemont C. Nat Commun. 2015 Nov 19;6:8882.doi: 10.1038/ncomms9882.


Optical volume and mass measurements show that mammalian cells swell during mitosis. Zlotek‐Zlotkiewicz E, Monnier S, Cappello G, Le Berre M and Piel M. J Cell Biol. 2015 Nov 23;211(4):765-74.doi: 10.1083/jcb.201505056.



Rab12 Localizes to Shiga Toxin-Induced Plasma Membrane Invaginations and Controls Toxin Transport. Gustaf E. Rydell, Henri-François Renard, Maria-Daniela Garcia-Castillo, Florent Dingli, Damarys Loew,Christophe Lamaze, Winfried Römer and Ludger Johannes. Traffic. 2014 Jul;15(7):772-87.doi: 10.1111/tra.12173. 


Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers. Ramya Lakshminarayan, ChristianWunder, Ulrike Becken, Mark T. Howes, Carola Benzing, Senthil Arumugam, Susanne Sales, Nicholas Ariotti, Valérie Chambon, Christophe Lamaze, Damarys Loew, Andrej Shevchenko, Katharina Gaus, Robert G. Parton and Ludger Johannes. Nat Cell Biol. 2014 Jun;16(6):595-606.doi: 10.1038/ncb2970.


Mutations of CEP83 Cause Infantile nephronophthisis and Intellectual Disability. Marion Failler, Heon Yung Gee, Pauline Krug, Kwangsic Joo, Jan Halbritter, Lilya Belkacem, Emilie Filhol, Jonathan D. Porath, Daniela A. Braun, Markus Schueler, Amandine Frigo, Olivier Alibeu, Cécile Masson, Karine Brochard, Bruno Hurault de Ligny, Robert Novo, Christine Pietrement, Hulya Kayserili, Remi Salomon, Marie-Claire Gubler, Edgar A. Otto, Corinne Antignac, Joon Kim, Alexandre Benmera, Friedhelm Hildebrandt and Sophie Saunier. Am J Hum Genet. 2014 Jun 5;94(6):905-14. doi: 10.1016/j.ajhg.2014.05.002.


Recycling Endosome Tubule Morphogenesis from Sorting Endosomes Requires the Kinesin Motor KIF13A. Cédric Delevoye, Stéphanie Miserey-Lenkei, Guillaume Montagnac, Floriane Gilles-Marsens, Perrine Paul-Gilloteaux, Francesca Giordano, Françoi Waharte, Michael S. Marks, Bruno Goud, and Graça Raposo. Cell Rep. 2014 Feb 13;6(3):445-54. doi: 10.1016/j.celrep.2014.01.002.


The CryoCapsule: Simplifying Correlative Light to Electron Microscopy. Xavier Heiligenstein, Jerome Heiligenstein, Cedric Delevoye, Ilse Hurbain, Sabine Bardin, Perrine Paul-Gilloteaux, Lucie Sengmanivong, Gilles Regnier, Jean Salamero, Claude Antony and Graca Raposo. Traffic. 2014 Jun;15(6):700-16.doi: 10.1111/tra.12164.


Cell adhesion defines the topology of endocytosis and signaling. Jean-Philippe Grossier, Georgia Xouri, Bruno Goud and Kristine Schauer. EMBO J. 2014 Jan 7;33(1):35-45.doi: 10.1002/embj.201385284. 


Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome. Emmanuelle Girard, Daniela Chmiest, Natalie Fournier, Ludger Johannes, Jean-Louis Paul,Benoit Vedie and Christophe Lamaze. Traffic. 2014 Mar;15(3):309-26. doi: 10.1111/tra.12143.


Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells.Nat. M. Reffay, M. C. Parrini, O. Cochet-Escartin, B. Ladoux, A. Buguin, S. Coscoy, F. Amblard, J. Camonis and P. Silberzan. Nat Cell Biol. 2014 Mar;16(3):217-23.doi: 10.1038/ncb2917.


ESCRT Machinery is required for plasma membrane repair. Ana Joaquina Jimenez, Paolo Maiuri, Julie Lafaurie-Janvore, Séverine Divoux, Matthieu Piel, Franck Perez. Science. 2014 Feb 28;343(6174):1247136.doi: 10.1126/science.1247136.


SLK-dependent activation of ERMs controls LGN–NuMA localization and spindle orientation. Mickael Machicoane, Cristina A. de Frutos, Jenny Fink, Murielle Rocancourt, Yannis Lombardi, Sonia Garel, Matthieu Piel and Arnaud Echard. J Cell Biol. 2014 Jun 23;205(6):791-9.doi: 10.1083/jcb.201401049.


Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling. Mathieu Boissan, Guillaume Montagnac, Qinfang Shen, Lorena Griparic, Jérôme Guitton, Maryse Romao, Nathalie Sauvonnet, Thibault Lagache, Ioan Lascu, Graça Raposo, Céline Desbourdes, Uwe Schlattner, Marie-Lise Lacombe, Simona Polo, Alexander M. van der Bliek, Aurélien Roux, Philippe Chavrier. Science. 2014 Jun 27;344(6191):1510-5.doi: 10.1126/science.1253768.


Compressive stress inhibits proliferation in tumor Spheroids through a volume limitation. Morgan Delarue, Fabien Montel, Danijela Vignjevic, Jacques Prost, Jean-François Joanny and Giovanni Cappello. Biophys J. 2014 Oct 21;107(8):1821-1828. doi: 10.1016/j.bpj.2014.08.031.


EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition. Audrey Clapéron, Martine Mergey, Thanh Huong Nguyen Ho-Bouldoires, Danijela Vignjevic, Dominique Wendum, Yves Chrétien, Fatiha Merabtene, Alexandra Frazao, Valérie Paradis, Chantal Housset, Nathalie Guedj, Laura Fouassier. J Hepatol. 2014 Aug;61(2):325-32. doi: 10.1016/j.jhep.2014.03.033.


BIN1/M-Amphiphysin2 induces clustering of phosphorinositides to recruit its downstream partner dynamin. Laura Picas, Julien Viaud, Kristine Schauer, Stefano Vanni, Karim Hnia, Vincent Fraisier, Aurélien Roux, Patricia Bassereau, Frédérique Gaits-Iacovoni, Bernard Payrastre, Jocelyn Laporte, Jean-Baptiste Manneville and Bruno Goud. Nat Commun. 2014 Dec 9;5:5647.doi: 10.1038/ncomms6647.


Mechanical role of actin dynamics in the rheology of the Golgi complex and in Golgi-associated trafficking events. David Guet, Kalpana Mandal, Mathieu Pinot, Jessica Hoffmann, Yara Abidine, Walter Sigaut, Sabine Bardin, Kristine Schauer, Bruno Goud, and Jean-Baptiste Manneville. Curr Biol. 2014 Aug 4;24(15):1700-11.doi: 10.1016/j.cub.2014.06.048.


Concomitant notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut. Maia Chanrion, Inna Kuperstein, Cédric Barrière, Fatima El Marjou, David Cohen, Danijela Vignjevic, Lev Stimmer, Perrine Paul-Gilloteaux, Ivan Bièche, Silvina Dos Reis Tavares, Giuseppe-Fulvio Boccia, Wulfran Cacheux, Didier Meseure, Silvia Fre, Loredana Martignetti, Patricia Legoix-Né, Elodie Girard, Luc Fetler, Emmanuel Barillot, Daniel Louvard, Andreï Zinovyev and Sylvie Robine. Nat Commun. 2014 Oct 8;5:5005.doi: 10.1038/ncomms6005.


Fascin plays a role in stress fiber organization and focal adhesion disassembly. Nadia Elkhatib, Matthew B. Neu, Carla Zensen, Kurt M. Schmoller, Daniel Louvard, Andreas R. Bausch, Timo Betz, and Danijela Matic Vignjevic. Curr Biol. 2014 Jul 7;24(13):1492-9.doi: 10.1016/j.cub.2014.05.023.


Adel Al Jord, Anne-Iris Lemaître, Nathalie Delgehyr, Marion Faucourt, Nathalie Spassky and Alice Meunier. Centriole amplification by mother and daughter centrioles differs in multiciliated cells. Nature. 2014 Dec 4;516(7529):104-7.doi: 10.1038/nature13770.


Control of MT1-MMP transport by atypical PKC during breast-cancer progression. Carine Rossé , Catalina Lodillinskya, Laetitia Fuhrmann, Maya Nourieh, Pedro Monteiro, Marie Irondelle, Emilie Lagoutte, Sophie Vacher, François Waharte, Perrine Paul-Gilloteaux, Maryse Romao, Lucie Sengmanivong, Mark Linch, Johan van Lint, Graça Raposo, Anne Vincent-Salomona, Ivan Bièche, Peter J. Parker, and Philippe Chavrier. Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1872-9.doi: 10.1073/pnas.1400749111.



C11ORF24 Is a Novel Type I Membrane Protein That Cycles between the Golgi Apparatus and the Plasma Membrane in Rab6-Positive Vesicles. Vincent Fraisier, Amal Kasri, Stéphanie Miserey-Lenkei, Jean-Baptiste Sibarita, Deepak Nair, Adeline Mayeux, Sabine Bardin, Yusuke Toyoda, Ina Poser, Andrei Poznyakovskiy, Bruno Goud,Anthony A. Hyman, Ariane Dimitrov. PLoS One. 2013 Dec 2;8(12):e82223.doi: 10.1371/journal.pone.0082223.


Identification and characterization of multiple novel Rab-myosin Va interactions. Andrew J. Lindsaya, Florence Jollivet, Conor P. Horgan, Amir R. Khan, Graça Raposod, Mary W. McCaffrey and Bruno Goud. Mol Biol Cell. 2013 Nov;24(21):3420-34.doi: 10.1091/mbc.E13-05-0236


The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II. Maria A. Rujano, Luis Sanchez-Pulido, Carole Pennetier, Gaelle le Dez and Renata Basto. Nat Cell Biol. 2013 Nov;15(11):1294-306.doi: 10.1038/ncb2858


Bug22 influences cilium morphology and the posttranslational modification of ciliary microtubules. Teresa Mendes Maia, Delphine Gogendeau, Carole Pennetier, Carsten Janke and Renata Basto. Biol Open. 2014 Feb 15;3(2):138-51.doi: 10.1242/bio.20146577.


Signaling events mediated by alpha3beta1 integrin are essential for mammary tumorigenesis. S Cagnet, MM Faraldo, M Kreft, A Sonnenberg, K Raymond and MA Glukhova. Oncogene. 2014 Aug 21;33(34):4286-95.doi: 10.1038/onc.2013.391.


Alpha-catenin, vinculin, and F-actin in strengthening E-cadherin cell-cell adhesions and mechanosensing. Dufour Sylvie, Mege Rene-Marc and Thiery Jean Paul. Cell Adh Migr. Jul-Aug 2013;7(4):345-50.doi: 10.4161/cam.25139.


VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites. Paola Larghi, David J Williamson, Jean-Marie Carpier, Stéphanie Dogniaux, Karine Chemin,Armelle Bohineust, Lydia Danglot, Katharina Gaus, Thierry Galli and Claire Hivroz. Nat Immunol. 2013 Jul;14(7):723-31.doi: 10.1038/ni.2609.


Centrosome amplification causes microcephaly. Véronique Marthiens, Maria A. Rujano, Carole Pennetier, Sarah Tessier, Perrine Paul-Gilloteaux and Renata Basto. Nat Cell Biol. 2013 Jul;15(7):731-40. doi: 10.1038/ncb2746.


Kinesin KIFC1 actively transports bare double-stranded DNA. Francesca Farina, Paolo Pierobon, Cedric Delevoye, Jordan Monnet, Florent Dingli,Damarys Loew, Maria Quanz, Marie Dutreix and Giovanni Cappello. Nucleic Acids Res. 2013 May;41(9):4926-37.doi: 10.1093/nar/gkt204


Arf1 and Membrane Curvature Cooperate to Recruit Arfaptin2 to Liposomes. Ernesto E. Ambroggio, James Sillibourne, Bruno Antonny, Jean-Baptiste Manneville, Bruno Goud. PLoS One. 2013 Apr 29;8(4):e62963. doi: 10.1371/journal.pone.0062963.


Imaging GTP-Bound Tubulin: From Cellular to In Vitro Assembled Microtubules. Helene de Forges, Antoine Pilon, Christian Pous and Franck Perez. Methods Cell Biol. 2013;115:139-53.doi: 10.1016/B978-0-12-407757-7.00010-4.


TRAIL protein localization in human primary T cells by 3D microscopy using 3D interactive surface plot: A new method to visualize plasma membrane. Christophe Gras, Nikaïa Smith, Lucie Sengmanivong, Mariana Gandini, Claire Fernandes Kubelka and Jean-Philippe Herbeuval. J Immunol Methods. 2013 Jan 31;387(1-2):147-56.doi: 10.1016/j.jim.2012.10.008.


Primary ciliogenesis requires the distal appendage component Cep123. James E. Sillibourne, Ilse Hurbain, Thierry Grand-Perret, Bruno Goud1, Phong Tran and Michel Bornens. Biol Open. 2013 Apr 9;2(6):535-45.doi: 10.1242/bio.20134457.


Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro. Kévin Alessandri, Bibhu Ranjan Sarangi, Vasily Valérïévitch Gurchenkova, Bidisha Sinhaf,Tobias Reinhold Kießling, Luc Fetler, Felix Ricoh, Simon Scheuringh, Christophe Lamaze, Anthony Simona, Sara Geraldoa, Danijela Vignjevic, Hugo Doméjean, Leslie Rolland, Anette Funfak, Jérôme Bibette, Nicolas Bremond and Pierre Nassoya. Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14843-8.doi: 10.1073/pnas.1309482110.


SNAP-Tagging the retrograde route. Ludger Johannes and Massiullah Shafaq-Zadah. Methods Cell Biol. 2013;118:139-55.doi: 10.1016/B978-0-12-417164-0.00009-4.


Sox10 and Itgb1 interactioninentericneuralcrestcellmigration. Yuli Watanabe, Florence Broders-Bondon, Viviane Baral, Perrine Paul-Gilloteaux, Veronique Pingault, Sylvie Dufour, Nadege Bondurand.Dev Biol. 2013 Jul 1;379(1):92-106.doi: 10.1016/j.ydbio.2013.04.013.


NaV1.5 Na+ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia. Lucie Brisson, Virginie Driffort, Lauriane Benoist, Mallorie Poet, Laurent Counillon, Ester Antelmi, Rosa Rubino, Pierre Besson, Fabien Labbal, Stephan Chevalier, Stephan J. Reshkin, Jacques Gore and Sébastien Roger . J Cell Sci. 2013 Nov 1;126(Pt 21):4835-42.doi: 10.1242/jcs.123901.


Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. Marina Colombo, Catarina Moita, Guillaume van Niel, Joanna Kowal, James Vigneron, Philippe Benaroch, Nicolas Manel, Luis F. Moita, Clotilde Théry, and Graça Raposo. J Cell Sci. 2013 Dec 15;126(Pt 24):5553-65.doi: 10.1242/jcs.128868


Cell adhesion defines the topology of endocytosis and signaling. Jean-Philippe Grossier, Georgia Xouri, Bruno Goud and Kristine Schauer. EMBO J. 2014 Jan 7;33(1):35-45.doi: 10.1002/embj.201385284.


ESCRT-III assembly and cytokinetic abscission Are Induced by Tension release in the intercellular bridge. Julie Lafaurie-Janvore, Paolo Maiuri, Irène Wang, Mathieu Pinot, Jean-Baptiste Manneville,Timo Betz, Martial Balland, Matthieu Piel. Science. 2013 Mar 29;339(6127):1625-9.doi: 10.1126/science.1233866.


aTAT1 catalyses microtubule acetylation at clathrin-coated pits. Guillaume Montagnac, Vannary Meas-Yedid, Marie Irondelle, Antonio Castro-Castro, Michel Franco, Toshinobu Shida, Maxence V. Nachury, Alexandre Benmerah, Jean-Christophe Olivo-Marin & Philippe Chavrier. Nature. 2013 Oct 24;502(7472):567-70.doi: 10.1038/nature12571.


Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. Pedro Monteiro, Carine Rossé, Antonio Castro-Castro, Marie Irondelle, Emilie Lagoutte, Perrine Paul-Gilloteaux, Claire Desnos, Etienne Formstecher, François Darchen, David Perrais, Alexis Gautreau, Maud Hertzog, and Philippe Chavrier. J Cell Biol. 2013 Dec 23;203(6):1063-79.doi: 10.1083/jcb.201306162.


BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells. Leila Rochina, Ilse Hurbaina, Lutgarde Serneels, Cecile Forta, Brenda Watt, Pascal Leblanc, Michael S. Marks, Bart De Strooperd, Graça Raposoa and Guillaume van Niela. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10658-63.doi: 10.1073/pnas.1220748110.


Enterocyte loss of polarity and gut wound healing rely upon the F-actin–severing function of villin. Florent Ubelmann, Mathias Chamaillard, Fatima El-Marjou, Anthony Simon, Jeanne Netter, Danijela Vignjevic, Buford L. Nichols, Roberto Quezada-Calvillo, Teddy Grandjean, Daniel Louvard, Céline Revenua and Sylvie Robine. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1380-9. doi: 10.1073/pnas.1218446110.



Atypical PKC is involved in breast tumor cell invasion through the control of MT1-MMP trafficking. C. Rosse, E. Lagoutte, M. Irondelle, M. Nourieh, F. Waharte, P. Monteiro, L. Sengmanivong, P. Paul-Gilloteaux, M.Romao, L. Fuhrmann, J. van Lint, G. Raposo, A. Vincent-Salomon, I. Bièche, P. Parker, P. Chavrier. Abstrract ASCB2012


Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages. Raphaël Gaudin, Bruna Cunha de Alencar, Mabel Jouve, Stefano Bèrre, Emmanuel Le Bouder, Michael Schindler, Aditi Varthaman, François-Xavier Gobert, and Philippe Benaroch. J Cell Biol. 2012 Oct 29;199(3):467-79.doi: 10.1083/jcb.201201144











Cytokine Secretion by CD4+ T Cells at the Immunological Synapse Requires Cdc42 dependent Local Actin Remodeling but Not Microtubule Organizing Center Polarity. Chemin K, Bohineust A, Dogniaux S, Tourret M, Guégan S, Miro F, Hivroz C. J Immunol. 2012 Sep 1;189(5):2159-68.doi: 10.4049/jimmunol.1200156


ATAT1/MEC-17 acetyltransferase and HDAC6 deacetylase control a balance of acetylation of alpha-tubulin and cortactin and regulate MT1-MMP trafficking and breast tumor cell invasion. Antonio Castro-Castroa, Carsten Jankea, Guillaume Montagnac, Perrine Paul-Gilloteauxa and Philippe Chavrier Eur J Cell Biol. Nov-Dec 2012;91(11-12):950-60.doi: 10.1016/j.ejcb.2012.07.001.


Cleavage of Toll-like receptor 3 by cathepsins B and His essential for signaling. Alejandra Garcia-Cattaneoa, François-Xavier Goberta, Mélanie Müllera, Florent Toscanod, Marcella Floresa, Aurianne Lescurea, Elaine Del Nerya and Philippe Benaroch. PNAS, vol. 109, no. 23, 9053–9058, June 5, 2012.


Sub-diffraction imaging on standard microscopes through photobleaching microscopy with nonlinear processing. Sebastian Munck, Katarzyna Miskiewicz, Ragna Sannerud, Silvia A. Menchon, Liya Jose,Rainer Heintzmann, Patrik Verstreken and Wim Annaert. J Cell Sci. 2012 May 1;125(Pt 9):2257-66.doi: 10.1242/jcs.098939.


A Rab11A/Myosin Vb/Rab11-FIP2 Complex Frames Two Late Recycling Steps of Langerin from the ERC to the Plasma Membrane. Gidon Alexandre, Bardin Sabine, Cinquin Bertrand, Boulanger Jerome, Waharte Francois, Heliot Laurent, de la Salle Henri, Hanau Daniel, Kervrann Charles, Goud Bruno and Salamero Jean. Traffic. 2012 Jun;13(6):815-33.doi: 10.1111/j.1600-0854.2012.01354.x.


Ubiquitylation of the nuclear pore complex controls nuclear migration during mitosis in S. cerevisiae. Hayakawa A, Babour Ana, Sengmanivong Lucie and Dargemont Catherine. J Cell Biol. 2012 Jan 9;196(1):19-27.doi: 10.1083/jcb.201108124.


Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration. Carine Rosse, Katrina Boeckeler, Mark Linch, Simone Radtke, David Frith, Karin Barnouin, Ali Sayed Morsi, Majid Hafezparast, Michael Howell and Peter J. Parker. J Cell Sci. 2012 Aug 15;125(Pt 16):3733-8.doi: 10.1242/jcs.089557.


Cytokine Secretion by CD4+ T Cells at the Immunological Synapse Requires Cdc42-Dependent Local Actin Remodeling but Not Microtubule Organizing Center Polarity. Karine Chemin, Armelle Bohineust, Stéphanie Dogniaux, Marie Tourret, Sarah Guégan, Francesc Miro, and Claire Hivroz. J Immunol. 2012 Sep 1;189(5):2159-68.doi: 10.4049/jimmunol.1200156.


Closed-form density-based framework for automatic detection of cellular morphology changes. Tarn Duong, Bruno Goud, and Kristine Schauer. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8382-7.doi: 10.1073/pnas.1117796109.


Ezrin Ubiquitylation by the E3 Ubiquitin Ligase, WWP1 and Consequent Regulation of Hepatocyte Growth Factor Receptor Activity. Rania F Zaarour, Dafne Chirivino, Laurence Del Maestro, Laurent Daviet, Azeddine Atfi, Daniel Louvard, Monique Arpin. PLoS One. 2012;7(5):e37490.doi: 10.1371/journal.pone.0037490.


Myosin VI Regulates Actin Dynamics and Melanosome Biogenesis. Sylvain Loubéry, Cédric Delevoye, Daniel Louvard, Graça Raposo and Evelyne Coudrier. Traffic. 2012 May;13(5):665-80.doi: 10.1111/j.1600-0854.2012.01342.x. 


An ARF6/Rab35 GTPase Cascade for Endocytic Recycling and Successful Cytokinesi. Laurent Chesneau, Daphné Dambournet, Mickaël Machicoane, Ilektra Kouranti, Mitsunori Fukuda, Bruno Goud and Arnaud Echard. Curr Biol. 2012 Jan 24;22(2):147-53.doi: 10.1016/j.cub.2011.11.058.


N-cadherin and β1-integrins cooperate during the development of the enteric nervous system. Florence Broders-Bondon , Perrine Paul-Gilloteaux, Camille Carlier, Glenn L. Radice , Sylvie Dufour.  Dev Biol. 2012 Apr 15;364(2):178-91.doi: 10.1016/j.ydbio.2012.02.001.




The first World Cell Race. Paolo Maiuri, Emmanuel Terriac,Perrine Paul-Gilloteaux,Timothée Vignaud, Krista McNally, James Onuffer, Kurt Thorn, Phuong A. Nguyen, Nefeli Georgoulia, Daniel Soong, Asier Jayo, Nina Beil, Jürgen Beneke, Joleen Chooi Hong Lim, Chloe Pei-Ying Sim, Yeh-Shiu Chu, WCR participants, Andrea Jiménez-Dalmaroni, Jean-François Joanny, Jean-Paul Thiery, Holger Erfle, Maddy Parsons,Timothy J. Mitchison, Wendell A. Lim, Ana-Maria Lennon-Duménil, Matthieu Piel and Manuel Théry. Curr Biol. 2012 Sep 11;22(17):R673-5.doi: 10.1016/j.cub.2012.07.052.


Force Generation upon T Cell Receptor Engagement. Julien Husson, Karine Chemin, Armelle Bohineust, Claire Hivroz, Nelly Henry. PLoS One. 2011 May 10;6(5):e19680.doi: 10.1371/journal.pone.0019680.


HDAC6 is required for invadopodia activity and invasion by breast tumor cells. Mercedes Reya, Marie Irondelle, François Waharte, Floria Lizarraga, Philippe Chavrier.Eur J Cell Biol. Feb-Mar 2011;90(2-3):128-35.doi: 10.1016/j.ejcb.2010.09.004


Polarized Secretion of Lysosomes at the B cell Synapse Couples Antigen Extraction to Processing and Presentation. Maria-Isabel Yuseff, Anne Reversat, Danielle Lankar,Jheimmy Diaz,Isabelle Fanget, Paolo Pierobon, Violaine Randrian, Nathanael Larochette, Fulvia Vascotto, Chantal Desdouets, Bertrand Jauffred, Yohanns Bellaiche, Stephane Gasman, François Darchen, Claire Desnos and Ana-Maria Lennon-Dumene. Immunity. 2011 Sep 23;35(3):361-74.doi: 10.1016/j.immuni.2011.07.008


MICAL-like1 mediates epidermal growth factor receptor endocytosis. Nancy Abou-Zeid, Rudy Pandjaitan, Lucie Sengmanivong, Violaine David, Gwenaelle Le Pavec, Jean Salamero and Ahmed Zahraoui.Mol Biol Cell. 2011 Sep;22(18):3431-41.doi: 10.1091/mbc.E11-01-0030.


Membrane tension regulates motility by controlling lamellipodium organization. Ellen L. Batchelder, Gunther Hollopeter, Clément Campillo, Xavier Mezangesa, Erik M. Jorgensend, Pierre Nassoy , Pierre Sensg, and Julie Plastino. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11429-34.doi: 10.1073/pnas.1010481108.


Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis. Daphné Dambournet, Mickael Machicoane, Laurent Chesneau, Martin Sachse, Murielle Rocancourt, Ahmed El Marjou, Etienne Formstecher, Rémi Salomon, Bruno Goud and Arnaud Echard. Nat Cell Biol. 2011 Jun 26;13(8):981-8.doi: 10.1038/ncb2279.


Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Claudia G. Almeida, Ayako Yamada, Danièle Tenza, Daniel Louvard, Graça Raposo and Evelyne Coudrier.Nat Cell Biol. 2011 Jun 12;13(7):779-89.doi: 10.1038/ncb2262.


A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates with the Vacuole in Saccharomyces cerevisiae. Svetlana Dokudovskaya, François Waharte, Avner Schlessinger, et al. Mol Cell Proteomics. 2011 Jun;10(6):M110.006478.doi: 10.1074/mcp.M110.006478


Decoupling of Activation and Effector Binding Underlies ARF6 Priming of Fast Endocytic Recycling. Guillaume Montagnac, Helene de Forges, Elizabeth Smythe, Charles Gueudry, Maryse Romao, Jean Salamero and Philippe Chavrier. Curr Biol. 2011 Apr 12;21(7):574-9.doi: 10.1016/j.cub.2011.02.034.


Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae. Bidisha Sinha, Darius Koster, Richard Ruez, Pauline Gonnord, Michele Bastiani, Daniel Abankwa,Radu V. Stan,Gillian Butler-Browne,Benoit Vedie, Ludger Johannes, Nobuhiro Morone,Robert G. Parton,Graça Raposo, Pierre Sens, Christophe Lamaze, and Pierre Nassoy. Cell. 2011 Feb 4;144(3):402-13.doi: 10.1016/j.cell.2010.12.031.


Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site. Anne Letessier , Gael A. Millot, Stephane Koundrioukoff, Anne-Marie Lachages, Nicolas Vogt R. Scott Hansen4, Bernard Malfoy, Olivier Brison & Michelle Debatisse.Nature. 2011 Feb 3;470(7332):120-3.doi: 10.1038/nature09745.


Control of mammary myoepithelial cell contractile function by a3b1 integrin signaling. Karine Raymond, Stephanie Cagnet,Maaike Kreft, Hans Janssen, Arnoud Sonnenberg and Marina A Glukhova. EMBO J. 2011 May 18;30(10):1896-906.doi: 10.1038/emboj.2011.113




A Patch-Based Method for Repetitive and Transient Event Detection in Fluorescence Imaging. Jerome Boulanger, Alexandre Gidon, Charles Kervran, Jean Salamero. PLoS One. 2010 Oct 15;5(10):e13190.doi: 10.1371/journal.pone.0013190


Microfluidic Sorting and Multimodal Typing of Cancer Cells in Self-Assembled Magnetic Arrays. Antoine-Emmanuel Saliba, Laure Saias, Eleni Psycharia, Nicolas Minc, Damien Simond, François-Clément Bidard, Claire Mathiot, Jean-Yves Pierga, Vincent Fraisier, Jean Salamero, Véronique Saada, Françoise Farace, Philippe Vielh, Laurent Malaquin and Jean-Louis Viovy. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14524-9.doi: 10.1073/pnas.1001515107


Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells. Renaud Colisson, Lucie Barblu, Christophe Gras, Franc¸oise Raynaud, Reda, Hadj-Slimane, Claudine Pique, Olivier Hermine, Yves Lepelletier and Jean-Philippe Herbeuval.Blood. 2010 Mar 18;115(11):2177-85.doi: 10.1182/blood-2009-06-224741.











HIiV-1 assembly in macrophages. Philippe Benaroch, Elisabeth Billard, Raphael Gaudin, Michael Schindler and Mabel Jouve , Benaroch et al.

Retrovirology. 2010 Apr 7;7:29.doi: 10.1186/1742-4690-7-29.


ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions. Ernesto Ambroggio, Benoît Sorre, Patricia Bassereau, Bruno Goud,Jean-Baptiste Manneville and Bruno Antonny. EMBO J. 2010 Jan 20;29(2):292-303.doi: 10.1038/emboj.2009.341.


Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication. James E. Sillibourne, Frederik Tack, Nele Vloemans, An Boeckx, Sathiesan Thambirajah, Pascal Bonnet, Frans C.S. Ramaekers, Michel Bornens and Thierry Grand-Perret. Mol Biol Cell. 2010 Feb 15;21(4):547-61.doi: 10.1091/mbc.e09-06-0505.


Probabilistic density maps to study global endomembrane organization. Kristine Schauer, Tarn Duong, Kevin Bleakley, Sabine Bardin, Michel Bornens and Bruno Goud. Nat Methods. 2010 Jul;7(7):560-6.doi: 10.1038/nmeth.1462.


Actin Dynamics Drive Membrane Reorganization and Scission in Clathrin-Independent Endocytosis. Winfried Römer, Le´ a-Laetitia Pontani, Benoît Sorre, Carles Rentero, Ludwig, Berland, Valérie Chambon, Christophe Lamaze, Patricia Bassereau, Cécile Sykes, Katharina Gaus and Ludger Johannes. Cell. 2010 Feb 19;140(4):540-53.doi: 10.1016/j.cell.2010.01.010.


Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. Marie Schoumacher, Robert D. Goldman, Daniel Louvard and Danijela M. Vignjevic J. Cell J Cell Biol. 2010 May 3;189(3):541-56.doi: 10.1083/jcb.200909113.



Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN. Arnoult N, Saintome C, Ourliac-Garnier I, Riou JF, Londoño-Vallejo A. Genes Dev. 2009 Dec 15;23(24):2915-24.doi: 10.1101/gad.544009


ESCRT-I Function is required for Tyrp1 Transport from Early endosomes to the elanosome LimitingMembrane. Steven T. Truschel, Sabrina Simoes, Subba Rao Gangi Setty, Dawn C. Harper,Danièle Tenza, Penelope C. Thomas,Kathryn E. Herman, Sara D. Sackett, David C. Cowan1, Alexander C. Theos, Grac¸a Raposo and Michael S. Marks. Traffic. 2009 Sep;10(9):1318-36.doi: 10.1111/j.1600-0854.2009.00955.x


Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londoño-Vallejo A.Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15726-31.doi: 10.1073/pnas.0907689106.


Endocytosis is required for E-cadherin redistribution at mature adherens junctions. Simon de Beco, Charles Gueudry, François Amblard and Sylvie Coscoy. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7010-5.doi: 10.1073/pnas.0811253106.


The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition. Francesca Giordano, Ciro Bonetti, Enrico M. Surace, Valeria Marigo and Graça Raposo. Hum Mol Genet. 2009 Dec 1;18(23):4530-45.doi: 10.1093/hmg/ddp415.


Scale space and variational methods in computer vision. A.Chessel, B. Cinquin, S. Bardin, J. Boulanger, J. Salamero and C. Kervrann. Proceeding Book Series: Lecture Notes in Computer Science, Vol.5567, 770-781, published: 2009.



COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension. Mannevillea JB, Casellab JF,  Ambroggioa E, Gounonc P, Bertheratd J, Bassereau P, Cartaudf J, Antonny B, and Goud.B. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16946-51.doi: 10.1073/pnas.0807102105